North American Registration Authorities Ontology
The registration authorities ontology provides the registration authorities, registries and related codes that are specific to the Canada, Mexico, and the United States that are needed for identification of substances and medicinal products.
The https://spec.pistoiaalliance.org/idmp/ontology/ISO/NorthAmericanJurisdiction/NorthAmericanRegistrationAuthorities.rdf version of this ontology was revised to normalize the use of hasTextualName from MVF rather than from LCC.
Note that jurisdiction-specific counterparties and codes are specified in subordinate ontologies supporting those jurisdictions.
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scientific society based in the United States that supports scientific inquiry in the field of chemistry
ISO 11238:2018 Health informatics - Identification of medicinal products (IDMP) - Data elements and structures for the unique identification and exchange of regulated information on substances, clause A.1.2
Founded in 1876 at New York University, the ACS has more than 155,000 members at all degree levels and in all fields of chemistry, chemical engineering, and related fields. It is one of the world's largest scientific societies by membership. The ACS is a 501(c)(3) non-profit organization and holds a congressional charter under Title 36 of the United States Code. Its headquarters are located in Washington, D.C., and it has a large concentration of staff in Columbus, Ohio.
American Chemical Society Registration Authority
American Chemical Society (ACS) in its role as a Registration Authority (RA), which is a function of the ACS for registration of substances in the CAS Registry
ISO 11238:2018 Health informatics - Identification of medicinal products (IDMP) - Data elements and structures for the unique identification and exchange of regulated information on substances, clauses 3.9, A.1.2
unique numerical identifier of a substance in the CAS Registry system
The numbers are sequential and are assigned as a substance enters the registry system. The numbers do not have a common length and lengths can be up to 10 digits. Each CAS number contains a single check digit. The assignment of chemical names is done according to the chemical nomenclature rules for CA index names, which is slightly different from the internationally standard IUPAC names, according to the rules of IUPAC.
Polymers frequently only have one CAS registry number associated with them, regardless of differences in molecular mass or other defining elements.
Although CAS numbers are widely used, they cannot be freely used. CAS has guidelines on the use of CAS registry numbers and has attempted to restrict their use in publicly available databases.
Centers for Disease Control and Prevention
Centers for Disease Control and Prevention Registration Authority
Centers for Disease Control and Prevention in its role as a Registration Authority (RA)
service that provides a periodical index that provides numerous tools such as SciFinder as well as tagged keywords, summaries, indexes of disclosures, and structures of compounds in recently published scientific documents
Approximately 8,000 journals, technical reports, dissertations, conference proceedings, and new books, available in at least 50 different languages, are monitored yearly, as are patent specifications from 27 countries and two international organizations. Chemical Abstracts ceased print publication on January 1, 2010.
registry that contains information on more than 130 million organic and inorganic substances, and more than 64 million protein and nucleic acid sequences
The sequence information comes from CAS and GenBank, produced by the National Institutes of Health. The chemical information is produced by CAS, and is prepared by the CAS Registry System, which identifies each compound with a specific CAS registry number, index name, and graphic representation of its chemical structure. The assignment of chemical names is done according to the chemical nomenclature rules for CA index names, which is slightly different from the internationally standard IUPAC names, according to the rules of IUPAC.
Chemical Abstracts Service registry entry
entry in the Chemical Abstracts Service (CAS) registry, prepared by the CAS Registry System, that identifies each compound with a specific CAS registry number, index name, and graphic representation of its chemical structure
database of privately and publicly funded clinical studies conducted around the world
independent scientific review board in the United States that reviews and assesses the safety of ingredients in an open, unbiased, and expert manner, and publishes the results in the peer-reviewed scientific literature
The Cosmetic Ingredient Review was established in 1976 by the industry trade association (then the Cosmetic, Toiletry, and Fragrance Association, now the Personal Care Products Council), with the support of the U.S. Food and Drug Administration and the Consumer Federation of America. Although funded by the Council, CIR, the Expert Panel for Cosmetic Ingredient Safety, and the review process are independent from the Council and the cosmetics industry. CIR and the Expert Panel for Cosmetic Ingredient Safety operate under a set of procedures.
repository that provides reviews and assesses the safety of ingredients in an open, unbiased, and expert manner, and publish the results in the peer-reviewed scientific literature
Cosmetic Ingredient Review Registration Authority
Cosmetic Ingredient Review (CIR) in its role as a Registration Authority (RA), for content that reflects the review and assessment of the safety of ingredients
Department of Agriculture Registration Authority
United States Department of Agriculture in its role as a Registration Authority (RA)
U.S. Department of Health and Human Services
online database containing information on drugs and drug targets
Food and Drug Administration Registration Authority
Food and Drug Administration (FDA) in its role as a Registration Authority (RA), which is a function of the G-SRS for registration of substances in the FDA/USP Global Substance Registry System
ISO 11238:2018 Health informatics - Identification of medicinal products (IDMP) - Data elements and structures for the unique identification and exchange of regulated information on substances, clause A.1.5
repository that documents animal, microbial, and plant collections through informational pages, searchable databases, and links to USDA-ARS projects that curate the collections
registry that was developed to assist regulators in managing substance information
GSRS was designed to facilitate global monitoring of human and animal medicinal, food, tobacco, and cosmetic products. GSRS provides unique substance identifiers consistent with the ISO 11238 standard. FDA's GSRS specifically generates the Unique Ingredient Identifiers (UNIIs) used in electronic listing and other regulatory activities.
Global Substance Registration System - GSRS
Global Substance Registry System registry entry
entry in the Global Substance Registry System (GSRS) registry, that includes the Unique Ingredient Identifiers (UNIIs) used in electronic listing and other regulatory activities
service with detailed business rules for data entry and generation of UNIIs for both simple and complex substances
Interagency Taxonomic Information System
registry that provides standardized information about the vascular plants, mosses, liverworts, hornworts, and lichens of the U.S. and its territories
The ITIS includes names, plant symbols, checklists, distributional data, species abstracts, characteristics, images, crop information, automated tools, onward Web links, and references. This information primarily promotes land conservation in the United States and its territories, but academic, educational, and general use is encouraged.
Integrated Taxonomic Information System registry entry
entry in the Integrated Taxonomic Information System registry comprised of a Taxonomix Serial Number used in electronic listing and other regulatory activities
group of agencies consisting of a steering committee and technical working committees for database design and quality management for the content provided in the Integrated Taxonomic Information System
These agencies signed a Memorandum of Understanding and have formed a Steering Committee that directs two technical work groups - the Database Work Group (DWG) and the Taxonomy Work Group (TWG). The DWG is responsible for the database design and overseeing development of the system to meet the requirements of the ITIS partners. The TWG is responsible for the quality and integrity of the database information. In addition to the database, the working groups have created "Taxonomic Workbench" software designed for easy entry and manipulation of taxonomic data.
Integrated Taxonomic Information System Registration Authority
Integrated Taxonomic Information System (ITIS) in its role as a Registration Authority (RA), which is multi-agency organization that involves specialists from around the world to assemble scientific names and their taxonomic relationships, and distribute that data through publicly available software
Integrated Taxonomic Information System Taxonomic Serial Number
unique identifier for an entry in the Integrated Taxonomic Information System registry used in electronic listing and other regulatory activities
Inventory of Effective Food Contact Substance Notifications
repository that lists effective pre-market notifications for food contact substances that have been demonstrated to be safe for their intended use
Inventory of Effective Food Contact Substance (FCS) Notifications
repository published by the U.S. National Library of Medicine (NLM) that provides up-to-date, unbiased and easily accessed information on the diagnosis, cause, frequency, clinical patterns and management of liver injury attributable to prescription and nonprescription medications and selected herbal and dietary supplements
LiverTox is also known as the Clinical and Research Information on Drug-Induced Liver Injury library.
National Library of Medicine (NLM) controlled vocabulary and thesaurus used for indexing articles for PubMed
entry in the Medical Subject Headings (MeSH) registry that includes the Medical Subject Headings Unique Identifier (MeSH Unique ID) used in electronic listing and other regulatory activities
medical subject headings unique identifier
alpha-numeric string that is used to identify records in the Medical Subject Headings registry
MeSH Unique ID finds Descriptor, Qualifier, and Supplemental Concept Records by their Record Unique Identifier.
institute that is part of the U.S. National Institutes of Health (NIH) that is the federal government's principal agency for cancer research and training
National Cancer Institute registration authority
National Cancer Institute in its role as a Registration Authority (RA)
registry that provides reference terminology for many NCI and other systems that is widely used across the healthcare industry as the basis for vocabulary and terminology work
It covers vocabulary for clinical care, translational and basic research, and public information and administrative activities.
National Cancer Institute Thesaurus Code
alpha-numeric string that is used to identify records in the National Center for Biotechnology Information Taxonomy registry
National Cancer Institute Thesaurus registry entry
entry in the National Cancer Institute Thesaurus that includes the National Cancer Institute Thesaurus Code used in electronic listing and other regulatory activities
National Center For Biotechnology Information
organization that is part of the U.S. National Library of Medicine, National Institutes of Health (NIH) that advances science and health by providing access to biomedical and genomic information
National Center for Biotechnology Information Gene Database
registry published by the National Center For Biotechnology Information that integrates information from a wide range of species
National Center For Biotechnology Information registration authority
National Center For Biotechnology Information in its role as a Registration Authority (RA)
National Center for Biotechnology Information Taxonomy Database
registry that is a curated classification and nomenclature for all of the organisms in the public sequence databases, representing roughly 10 percent of the described species of life on the planet
National Center for Biotechnology Information Taxonomy Database registry entry
entry in the National Center for Biotechnology Information Taxonomy Database, that includes the National Center for Biotechnology Information Taxonomy Database Unique Identifier used in electronic listing and other regulatory activities
National Center for Biotechnology Information Taxonomy identifier
National Drug File - Reference Terminology
legacy registry that was published by the U.S. Department of Veterans Affairs, Veterans Health Administration, providing standard names for (1) mechanism of action, (2) Physiologic Effect and (3) Structural Class for drugs NDF-RT is part of the Federal Medication Terminologies.
NDF-RT is part of the Federal Medication Terminologies. Publication of NDF-RT has ended. The Medication Reference Terminology (MED-RT) is the evolutionary successor to the Veterans Health Administration National Drug File.
National Drug File - Reference Terminology (NDF-RT)
U.S. government institute that is part of the National Institutes of Health, responsible for collecting, curating and providing access to medicinal and related scientific publications
National Library of Medicine Registration Authority
National Library of Medicine (NLM) in its role as a Registration Authority (RA)
organization within the U.S. Department of Agriculture that focuses on plant data collection, content, quality control, integration, dissemination, and interpretation for National Resources Conservation Service (NRCS) use in conservation practices
party that was a spin-off from work conducted by the University of Alberta to manage products related to the DrugBank repository
OMx Personal Health Analytics, Inc. as registration authority
OMx Personal Health Analytics in its role as the registration authority for the DrugBank Online repository
orphan drug product designation database
Orphan Drug Product designation database
registry published by the U.S. Environmental Protection Agency that contains information concerning all pesticide products registered in the United States
Plant List of Accepted Nomenclature, Taxonomy, and Symbols
registry published by the U.S. Department of Agriculture that provides standardized information about the vascular plants, mosses, liverworts, hornworts, and lichens of the U.S. and its territories
The registry includes names, plant symbols, checklists, distributional data, species abstracts, characteristics, images, crop information, automated tools, onward Web links, and references. This information primarily promotes land conservation in the United States and its territories, but academic, educational, and general use is encouraged.
Plant List of Accepted Nomenclature, Taxonomy, and Symbols entry
entry in the Plant List of Accepted Nomenclature, Taxonomy, and Symbols registry used in electronic listing and other regulatory activities
Plant List of Accepted Nomenclature, Taxonomy, and Symbols symbol
unique identifier for an entry in the Plant List of Accepted Nomenclature, Taxonomy, and Symbols registry used in electronic listing and other regulatory activities
registry that is an open chemistry database at the National Institutes of Health (NIH)
registry published by the U.S. National Library of Medicine that provides normalized names for clinical drugs and links its names to many of the drug vocabularies commonly used in pharmacy management and drug interaction software, including those of First Databank, Micromedex, and Gold Standard Drug Database
By providing links between these vocabularies, RxNorm can mediate messages between systems not using the same software and vocabulary.
all-online compendium that provides monographs and reference materials for chemical and biological medicines and excipients legally marketed in any country
10-character, randomly generated alpha-numeric string that is used to identify substances in medicinal products in the FDA Global Substance Registration System (G-SRS)
The first nine characters are randomly generated followed by a check character. The integrity check on the UNII is stronger than both the EC# and the CAS Registry Number because of the random generation from a large number of potential UNIIs and the fact that there are 36 possible check characters compared to 10 with both the EC# and CAS Registry Number.
The UNII is freely available for use and there is a mechanism whereby a manufacturer can petition for the generation of a UNII through the FDA. The system has the capability for both public and restricted access to information, and can be adapted to produce specified substance identifiers.
University of California, San Franciso Federal Drug Administration TransPortal
standardized and publicly accessible website for archiving and disseminating information on mammalian transporter interactions with xenobiotics, including pharmaceuticals and environmental chemicals
U.S. government healthcare organization that provides primary care, specialized care, and related medical and social support services to American veterans
Veterans Health Administration Registration Authority
Veterans Health Administration in its role as a Registration Authority (RA)